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Isotonix® Digestive Enzymes

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In today’s world of processed and fast foods, the body must work harder to break down food and absorb the nutrients. Isotonix Digestive Enzymes, an isotonic-capable food supplement, contains DigeZyme ® , a multi-enzyme blend of amylase, protease, cellulase, tilactase, and lipase, and additional Amylase, which are formulated to replenish essential digestive enzymes, contributing to good digestive health. Isotonix Digestive Enzymes promotes digestion and absorption of nutrients, supports a healthy digestive tract, and may help ease occasional stomach upset. The enzymes in this complex are of microbial origin (fungal amylase, lipase, lactase, cellulose and protease). The product is therefore entirely of non-animal origin. Enzymes are important for the body’s proper absorption and utilisation of food. Over time, the body’s ability to make certain enzymes decreases as part of the natural aging process. Many scientists now believe that maintaining normal levels of key enzymes is important to maintaining overall health. Enzymes are responsible for every activity of life. Digestive and metabolic are the two primary classifications of enzymes within the body. Proteases (aid in digesting protein), amylases (aid in digesting carbohydrates), and lipases (aid in digesting fats) are the three primary digestive enzymes, which function as the biological catalyst to breaking down food.
  • Aids digestion
  • Provides enzymes that promote the absorption of nutrients
  • Supports a healthy digestive tract
  • Supports healthy immune functions
  • May help ease occasional stomach upset
  • Protease enzyme helps in the digestion of gluten-containing food such as wheat and related cereal
  • This vegetarian product contains no added wheat, soy, yeast, gluten, artificial flavour, salt, preservatives or milk
  • Offered with the fastest and most efficient delivery system of all nutraceuticals

Amylase
Our formula uses Amylase within the DigeZyme ® multi-enzyme complex as well as added amylase to assist more with digesting carbohydrates. Amylases are enzymes that catalyze the hydrolysis of alpha-1, 4-glycosidic linkages of polysaccharides to yield dextrins, oligosaccharides, maltose and D-glucose. Amylases are derived from animal, fungal and plant sources. There are several different amylases. These enzymes are classified according to the manner in which the glysosidic bond is attacked. Alpha-amylases hydrolyze alpha-1, 4-glycosidic linkages, randomly yielding dextrins, oligosaccharides and monosaccharides. Alpha-amylases are endo-amylases. Exoamylases hydrolyze the alpha-1, 4-glycosidic linkage only from the non-reducing outer polysaccharide chain ends. Exoamylases include beta-amylases and glucoamylases (gamma-amylases, amyloglucosidases). Beta-amylases yield beta-limit dextrins and maltose. Gamma-amylases yield glucose. Amylases are used as digestants. Amylase activity is expressed as Dextrinizing Units or DU.

Protease

Proteases are enzymes that break peptide bonds between amino acids in proteins. The process is called proteolytic cleavage, a common mechanism of activation or inactivation of enzymes especially involved in blood coagulation or digestion. They use a molecule of water for this and are thus classified as hydrolases. Proteases occur naturally in all organisms and constitute one to five percent of the gene content. These enzymes are involved in a multitude of physiological reactions from simple digestion of food proteins to highly regulated cascades (e.g. the blood clotting cascade, the complement system, apoptosis pathways and the invertebrate prophenoloxidase activating cascade). Peptidases can break either specific peptide bonds ( limited proteolysis ), depending on the amino acid sequence of a protein, or break down a complete peptide to amino acids ( unlimited proteolysis ). The activity can be a destructive change abolishing a protein's function or digesting it to its principal components, an activation of a function or a signal in a signalling pathway.

Lipase

A lipase is a water-soluble enzyme that catalyses the hydrolysis of ester bonds in water–insoluble, lipid substrates. Most lipases act at a specific position on the glycerol backbone of a lipid substrate (A1, A2 or A3). In the example of human pancreatic lipase (HPL), which is the main enzyme responsible for breaking down fats in the human digestive system, a lipase acts to convert triglyceride substrates found in oils from food to monoglycerides and free fatty acids. Pancreatic lipases are found in the spaces outside of cells and have roles in the metabolism, absorption and transport of lipids throughout the body. Lipases are involved in diverse biological processes ranging from routine metabolism of dietary triglycerides to cell signalling and inflammation. Several different types of lipases are found in the human body, including pancreatic lipase, hepatic lipase, lysosomal lipase, gastric lipase, endothelial lipase and as various phospholipases.

Cellulase

Cellulase is an enzyme that breaks down cellulose to beta-glucose. Most animals (including humans) do not produce cellulase in their bodies, and are therefore unable to use most of the energy contained in plant material. Cellulase is an enzyme derived from the fungi Aspergillus niger and Trichoderma longbrachiatum or other sources. Cellulose is an indigestible plant polysaccharide. It is the principal constituent of the cell wall of plants. Cellulase has cellulolytic activity, meaning that it hydrolyses cellulose. Cellulase hydrolyses the beta-D-1, 4-glycosidic bonds of cellulose. Cellulase is used as a digestive aid, particularly in animals, and for the management of flatulence. The activity of cellulase is expressed in cellulose units or CU.


Tilactase (Lactase)
Tilactase is a sugar-splitting enzyme that hydrolyzes lactose, a milk sugar, to produce glucose and galactose. In humans, tilactase is present predominantly along the brush border membrane of the differentiated enterocytes lining the villi of the small intestine. Tilactase is essential for the digestion of lactose in milk. Deficiency of the enzyme causes lactose intolerance. Symptoms of lactose intolerance include abdominal bloating and cramps, flatulence, diarrhea and nausea.

What are digestive enzymes?
Digestive enzymes are special catalytic proteins that help your body break down food to utilise the complete spectrum of nutrients in the food we eat. Isotonix Digestive Enzymes acts to supplement and maximise the activity of the body’s own enzymes in an easy-to-take, pleasant-tasting drink. Our lifestyles and diets are constantly changing. If the last 25 years are any indication, these changes are not usually for the best. Foods that would otherwise offer us their own added enzymes to help our bodies absorb more nutrients are increasingly processed, heated for extended shelf life and stripped of vital elements. The problem is that in making increasing numbers of foods “safe” for ingestion, we are in some cases making foods less healthy for our systems. Isotonix Digestive Enzymes provides the body with additional, essential enzymes necessary for maximum absorption of nutrients from the food we eat.

How do enzymes work in the body?
Enzymes are the workhorses of our cells. They are proteins that catalyse many thousands of biochemical reactions in the body. While most enzymes work inside our cells, digestive enzymes operate outside the cells in the gastrointestinal tract. The start of digestion begins with digestive enzymes secreted by salivary gland cells into our mouths. Cells lining the gastrointestinal tract also contribute enzymes such as pepsin in the stomach. In addition, digestive enzymes are produced in the pancreas and are emptied into the upper part of the small intestine. These enzymes help to break apart proteins, allowing the body to optimise its effort to digest proteins from plant and animal sources as well as break down starch, lactose, fats, and nucleic acids (DNA and RNA). The result is a more complete digestive process, resulting in better nutritional absorption. Isotonix Digestive Enzymes supplies enzymes that are not inactivated by stomach acid. What this means is that the supplemental enzymes mix with and work in concert with the ingested food and begin to work with the body’s own digestive enzymes to release as many of the nutrients as possible.

What happens when we eat?
Even before we eat our body’s digestive action begins to take place. Simply smelling food activates our salivary glands (“mouth watering”). As the food enters the stomach, the stomach acid and pepsin work together to begin breaking the food down into material the small intestine (where most nutrients are absorbed) can use. Enzymes specific to each of the three nutrient groups are released at this stage, further breaking down the food and contributing to the digestive and absorption processes. These processes continue into the large intestine until the food’s nutritional content is extracted by the body.

Who should use Isotonix Digestive Enzymes?

Isotonix Digestive Enzymes is a beneficial supplement for all adults (18 years and over) looking to support their digestive health, especially those whose lifestyle consists of processed and fast foods. This is because such foods require the body to work harder to break down processed foods.

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